As giant cell tumor can be cured?
Giant cell tumor most often appears in people aged 18 to 40 years. Women fall ill more often than men. Giant cell tumor can develop in the form of benign neoplasm, but under certain circumstances it is converted into a malignant tumor. Its medical name – osteoblastoclastoma. Usually the growth of such lesions begins in the final divisions on the bone, but then they can go and in the related field.
Symptoms of the disease and its causes
In most cases such a tumor for a long time itself does not show. Since this type of lesion at the initial stage is a benign tumor, many patients have metastases even penetrated into lung tissue, no sensation do not cause. But many patients notice the pain of bone structures, especially if the affected bone structure at the hips or sacrum.
Jaw lesions characteristic of adolescence. Most commonly affected are the lower, movable part of the jaw. The disease is asymptomatic for 3-7 years. On the site of the lesion molars occurs a swelling that grows over time. During her studies in an x-ray detected structures with many voids, and in the place where the patient had the tooth root, typically, grows a cyst.
Lesions on the legs and in the lumbar spine suffer more than women, especially pregnant women. In the field of education for such injuries, there is usually some slight swelling. Soreness can occur at the joints when increasing physical load.
If there is a different bone structure, the damage can spread to her – this often happens with the localization of the primary focus on the sacrum. When this begins to break down the basis of the bones, and develop metastases, which penetrates into the less dense region of the patient's body. During this process can be the conversion – the swelling of soft tissues caused by metastases, is transformed into malignant cancer lesions with corresponding symptoms.
Pain may manifest in the patient as during movement and at rest, for example, when a person sits.
Most Often with giant cell tumor localization of damaged areas it is found in the articular ends of long tubular bones, and half of the patients affected area around the knee.
Typically, the diagnosis of giant cell tumors in 12% of patients occurs after they reach a health facility for help with the fracture, during which there was minor damage.
This kind of disease belongs to the group of benign tumors, but if you increase the size of the lesion usually is the destruction of bone structures and the appearance of metastases that spread to other organs of the patient.
Osteoblastoclastoma Usually consists of two types of cells – the first are giant entities with a large number of cores, and the latter has a single core structure. The second type according to the doctors, and causes the growth of tumors and destruction of bone structures. Mainly affects the knee, Shin and shoulder bones. Less under the impact of the disease fall edge, sacral-lumbar, jaw, spine.
For detection of giant cell tumor x-ray equipment which helps to determine the place the hearth began the destruction in the immediate area of long tubular bone structures. After this is done, biopsy of the primary site of the lesion or metastasis, if x-rays showed their presence. This is done in order to determine whether regenerated the tumour in a malignant tumor or not. After receipt and processing of all patient's examination data doctors plan ways of dealing with the disease.
How to treat this type of tumor?
The Main way to eradicate the disease is prompt surgical intervention.
Doctors perform surgery that resection (cutting out) of damaged areas. Then plastic is introduced defect. If the tumor has invaded a large amount, there shall be an endoprosthesis. After that, patients are under the supervision of the attending physician, to identify a relapse. If localization of the lesion identified on the rump, instead of surgery for resection of these zones, the doctors sent the patient to radiation therapy. Often on the table to the surgeons with lesions in the hips and sacrum are pregnant women. To treat them it is necessary in some cases to terminate the pregnancy.
After surgery to removegiant cell tumors can occur a complication in the form of development of recurrent disease, but with signs of malignancy. This usually happens when the first operation removed all the parts of the affected areas or radiation therapy was carried out poorly.
Lesions in the jaw are also cured with the help of surgery. Surgeons cut out the main body of the tumor. Radiation therapy in this type of the disease ineffective. The outcome of treatment for giant cell tumor the majority of human cases if timely surgical intervention is favorable.
In practice, many patients begin a normal life within 1-3 months after the resection or radiation therapy if the lesion does not develop into a malignant counterpart.